Focusing on the Parents, esp. the Mother
Most of what We Know comes from the Second Episode of the Third Season (see below) and Third Episode and it is still on the Spoilers page until each air in the U.S.

   

From "The Sign of Three", Mrs. Hudson discovers Sherlock dancing the morning of John's wedding. He is finishing the composition of the wedding waltz he is writing for them. He asks her, "Why are you here?"
    "I’m bringing you your morning tea. You’re not usually awake."
    "You bring me tea in the morning?"
    "Well, where d’you think it came from?"
    "I don’t know. I just thought it sort of happened."
    "Your mother has a lot to answer for."
    "Mm, I know. I have a list. Mycroft has a file."
    After a brief conversation, Sherlock gets rid of Mrs. Hudson demending that she go out for biscuits, she says, "I really am going to have a word with your mother."
    "You can if you like. She understands very little."
Mrs. Holmes wrote a book titled The Dynamics of Combustion by M. L. Holmes (so it must have been written after her marriage). Sherlock's father says of her, "Complete flake, my wife, but happens to be a genius" and also "unbelievably hot." She refers to the book as "that silly old thing". — source: "His Last Vow"

Sherlock (Benedict Cumberbatch) on far left and Mycroft (Mark Gatiss) on the right
with Mrs. & Mr. Holmes (Wanda Ventham and Timothy Carlton, Cumberbatch's real parents)
Characters: Sherlock Holmes || Dr. John H. Watson || The Friendship between Sherlock & John || Mycroft Holmes || Sherlock & Mycroft || Mrs. Hudson
Irene Adler || Mary Watson (nee Morstan) ||  DI Greg Lestrade || The Holmes Family Dynamics || 221 Baker St. || St. Bartholomew's Hospital || Sherlock's Coat


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